prof. Anne Vral (PhD)
Principal investigator radiobiology group
Associate professor (Faculty of Medicine and Health Sciences, UGent)
Research focus
The main focus of the research team is in in the field of basic and medically applied (radiation diagnostics and radiotherapy) radiobiology, radiation protection, biological dosimetry and cancer. The topics related to cancer are dealing with radiosensitivity, the underlying DNA double strand break repair mechanisms (homologous recombination and non-homologous end-joining) and the link with cancer predisposition esp. breast cancer (BRCA1&2). The expertise covers a broad range of technologies used to study effects of radiation such as cytogenetic assays (microcnucleus assay, dicentric assay), cell culture techniques, immunohistochemistry, apoptosis, DNA repair foci assays, SNP analysis, western blotprotein expression, etc.
Research team
- Prof. Anne Vral - principle investigator, full professor
- Prof. Ans Baeyens - principle investigator, associate professor
- Lama Ramadan - doctoral fellow
- Leen Pieters - technician
- Toke Thiron - technician
Key publications
- 2023. “RENEB Inter-Laboratory Comparison 2021 : The Cytokinesis-Block Micronucleus Assay.” RADIATION RESEARCH 199 (6): 571–582. doi:10.1667/rade-22-00201.1.
- 2023. “International Comparison Exercise for Biological Dosimetry after Exposures with Neutrons Performed at Two Irradiation Facilities as Part of the BALANCE Project.” CYTOGENETIC AND GENOME RESEARCH 163 (3–4): 163–177. doi:10.1159/000530728.
- 2023. “Atm Deficient Zebrafish Model Reveals Conservation of the Tumour Suppressor Function and a Role in Fertility.” GENES & DISEASES. Elsevier BV. doi:10.1016/j.gendis.2022.04.023.
- 2023. “Impact of Proton Therapy on the DNA Damage Induction and Repair in Hematopoietic Stem and Progenitor Cells.” SCIENTIFIC REPORTS 13 (1). doi:10.1038/s41598-023-42362-0.
- 2022. “An Updated View into the Cell Cycle Kinetics of Human T Lymphocytes and the Impact of Irradiation.” SCIENTIFIC REPORTS 12 (1). doi:10.1038/s41598-022-11364-9.
- 2021. “The Cytokinesis-Block Micronucleus Assay for Cryopreserved Whole Blood.” INTERNATIONAL JOURNAL OF RADIATION BIOLOGY 97 (9): 1252–1260. doi:10.1080/09553002.2021.1941378.
Contact & links
- Lab address: Department Human Structure and Repair, Radiobiology Lab, Campus UZGent, entrance 46, building 6B3, UZP123, Corneel Heymanslaan 10, 9000 Gent
- Autobeeldanalyse
- Biodosimetrie