prof. Wim Ceelen (MD, PhD)

CRIG group leader
WimCeelen

Full professor, Department of Surgery, Ghent University
Director, Experimental Surgery lab, Ghent University
Senior staff, GI Surgery, Ghent University Hospital

 

Research focus

The main research interests of the group are:
- Peritoneal carcinomatosis and intraperitoneal drug delivery
- Vascular effects of radiotherapy in GI cancer

Biography

Wim P Ceelen graduated as a medical doctor in 1992 at Ghent University and later obtained his PhD at the same university with a doctoral thesis entitled 'Neoadjuvant multimodal therapy in rectal cancer'. Currently, he is a senior surgeon in the department of Gastrointestinal Surgery at the Ghent University Hospital and was appointed as Full Professor in surgical oncology at Ghent University. He is a Senior Clinical Investigator with the FWO – Vlaanderen and is director of the Laboratory of Experimental Surgery at Ghent University. Dr Ceelen has an interest in surgical oncology of the digestive tract. His research includes functional and molecular imaging in animal tumor models and new approaches to intraperitoneal drug delivery. He is (co)author of over 100 A1 publications and promoter of 3 completed and three ongoing PhD projects. He is president of the Belgian Society of Surgical Oncology and board member of the European Society for Surgical Research. He is a member of the EORTC GI group, the Cochrane collaboration GI group, the Society of Surgical Oncology (SSO), ESSO, and the American College of Surgeons. Dr Ceelen is Editor-in -chief of Acta Chirurgica Belgica and associate editor of European Surgical Research and Frontiers in Surgical Oncology. He was granted membership of the Royal Belgian Academy of Medicine in 2012.

Research team

  • prof. dr. Wim Ceelen - principal investigator, full professor
  • prof. Wouter Willaert (MD, PhD) - director ITCIT
  • dr. Sarah Cosyns - post-doctoral fellow
  • Charlotte Carlier - doctoral fellow
  • Leen van de Sande - doctoral fellow
  • Félix Gremonprez - doctoral fellow
  • Elodie Melssens - doctoral fellow
  • Mohammad Rahimi Gorji - doctoral fellow
  • Natacha Rosseel - technician

Key publications

  • Assessment of Ovarian Cancer Tumors Treated with Intraperitoneal Cisplatin Therapy by Nanoscopic X-ray Fluorescence Imaging. Sci Rep, 2016 (PMID: 27444797)
  • Nanomedicine-based intraperitoneal therapy for the treatment of peritoneal carcinomatosis - Mission possible? Adv Drug Deliv Rev, 2016 (PMID: 27422808)
  • Effect of Neoadjuvant Radiation Dose and Schedule on Nodal Count and Its Prognostic Impact in Stage II-III Rectal Cancer. Ann Surg Oncol, 2016 (PMID: 27380639)
  • Genipin-crosslinked gelatin microspheres as a strategy to
  • prevent postsurgical peritoneal adhesions: In vitro and in vivo characterization. Biomaterials, 2016 (PMID: 27135715)
  • Pretreatment with VEGF(R)-inhibitors reduces interstitial fluid pressure, increases intraperitoneal chemotherapy drug penetration, and impedes tumor growth in a mouse colorectal carcinomatosis model. Oncotarget, 2015 (PMID: 26375674)

Contact & links