prof. Sylvie Rottey (MD, PhD)
Head of Department of Medical Oncology
Head of the Drug Research Unit Ghent - especially performing phase I trials first in humans - healthy volunteers and cancer patients
Medical Oncologist
MD Specialist in Clinical Pharmacology and Pharmaceutical Medicine
UGent : Department of Fundamental and Applied Medical Science GE33
Member of recognition committee and Internships for Clinical Pharmacology/Pharmaceutical Medicine - UGent
Research focus
For the last twenty years, prof. dr. Rottey is involved in international high-level research towards novel therapeutic options for patients with various solid tumors As prof. dr. Rottey is leading phase I oncology clinical trials for more than a decade, she has worked and continues to work with different immunotherapies in development, antibody drug conjugates, T-cell therapies, biomarker based treatments,… .
Prof. dr. Rottey is promotor for the doctorate of:
- dr. Alexander Decruyenaere (MD) – co-investigator, doctoral fellow, 2022 - ongoing: 'The Real Deal Behind the Artificial Appeal: Inferential Utility of Tabulator Synthetic Data'
- dr. Daan De Maeseneer (MD) – co-investigator, doctoral fellow, 2020 – ongoing: 'Evaluating bladder cancer genetics as predictive and prognostic biomarkers'
- Lissa Eggermont – doctoral fellow, 2023 – ongoing: 'Urine N-glycosylation as biomarker for prostate cancer: optimalisation of preanalytic conditions and correlation to clinical parameters in the differential diagnosis of prostate cancer'
- dr. Michael Saerens (MD) – co-investigator, doctoral fellow, 2022 – ongoing: 'Tumor-associated macrophages in head and neck squamous cell carcinoma: association with CD8+ tumor-infiltrating T-lymphocytes and impact on survival'
- Li Shoabo – doctoral fellow, 2024 – ongoing: 'SSTR-2 expression on tumor-associated macrophages in solid malignancies – predictive and prognostic value in patients receiving immune-checkpoint inhibitors'
- Mathieu Spaas – doctoral fellow, 2020 – ongoing: 'Checkpoint inhibitors in combination with stereotactic body radiotherapy in patients with advanced solid tumours'
- dr. Eufra Van Damme (MD) - doctoral fellow, 2021 – ongoing: 'Prediction of immunotherapy response and toxicity in melanoma, renal cell and lung cancer using transcriptome based systemic immune phenotyping'
Biography
- Medical doctor, Ghent University, 1993-2000
- Board certificate of internal medicine, 2002
- Medical Oncology, 2003
- PhD: Doctor in Medical Science, 99mTc-HYNIC Annexin-V for monitoring response to chemotherapy: methodology and feasibility studies, 2007
- Professor in Pharmacology, 2011
- Head of Drug Research Unit Ghent , 2015
- Head of Department of Medical Oncology, 2000
- MD in clinical pharmacology and pharmaceutical medicine, 2024
Research team
- prof. Sylvie Rottey (MD, PhD) – principal investigator
- Team members of the medical staff department of Medical Oncology:
• dr. Alexander Decruyenaere (MD) – co-investigator, doctoral fellow
• prof. Hannelore Denys (MD, PhD) – principal investigator, co-investigator
• dr. Daan De Maeseneer (MD) – co-investigator, doctoral fellow
• dr. Elien De Mulder (MD) – co-investigator
• dr. Aglaja De Pauw (MD) – co-investigator
• dr. Ingeborg Hilderson (MD) – co-investigator
• dr. Justine Himpe (MD) – co-investigator
• dr. Celine Jacobs (MD) – principal investigator, co-investigator
• prof. Lore Lapeire (MD, PhD) – principal investigator, co-investigator
• dr. Eline Naert (MD) – principal investigator, co-investigator, doctoral fellow
• dr. Michael Saerens (MD) – principal investigator, co-investigator, doctoral fellow
• dr. Tijl Vermassen (PhD) – post-doctoral researcher
- Team D.R.U.G, investigators:
• dr. Brant Delafontaine (MD) – co-investigator
• dr. Greet Schelfaut (MD) – co-investigator
• dr. Griet Van Lancker (MD) – co-investigator
• dr. Jasper Vogels (MD) – co-investigator
- Team D.R.U.G, teamlead:
• Elke Colman, teamlead Safepedrug Clinical Trial Unit
• Katrijn Criel, teamlead Drug Research Unit Ghent
• Adelheid Hollebosch, teamlead Drug Research Unit Ghent
• Carla Vandenabeele, teamlead Drug Research Unit Ghent
Key publications
Find all publications of prof. Rottey via Ghent University Academic Bibliography or PubMed
Contact
- drug@uzgent
- sylvie.rottey@UGent.be or sylvie.rottey@uzgent.be
- D.R.U.G.: UZ Gent, C. Heymanslaan 10, Nobel, entrance 7, route 7030, 9000 Gent
- Medical Oncology Department: UZ Gent, C. Heymanslaan 10, entrance 50, route 554, 9000 Gent