Gabriele Ferrari
Doctoral fellow – Tissue engineering and Biomaterials Group, Department of Human Structure and Repair (Faculty of Medicine and Health Sciences - UGent)
Principal investigator: prof. Ruslan Dmitriev (PhD)
Research focus
Live cell imaging is a powerful tool to investigate complex in-vitro models like tumor and stem cells spheroids, organoids, and microfluidic devices.
Our team develops optical biosensors and imaging strategies for quantitative measurements of different biomarkers in 3D complex models. Using time resolved fluorescence imaging we aim to map oxygen gradients in vitro, multiplexed with measures of NAD(P)H, FAD, pH, glucose, temperature and Ca2+, important for the correct modelling of the tumor microenvironment.
Additionally, we are developing advanced biomaterials for 3D printed constructs able to sense oxygen levels and control oxygen release, compatible with multiplexed fluorescence imaging.
Further applications of these strategies include direct imaging of the tumor microenvironment in vivo and implanted tissues.
Biography
I obtained a master’s and bachelor’s degree in biomedical engineering at Politecnico di Milano (Italy) with specialization in Bioengineering for Cells, Tissues and Biotechnologies. I worked in the field of advanced in-vitro models, millifluidic and microphysiological systems. At Imperial College London I worked on advanced biomaterials for heart regeneration and wound healing. I joined Prof. Ruslan I. Dmitriev in September 2023 at Ghent University to start my PhD within the Marie Skłodowska-Curie Actions – Doctoral Network “FLIMagin3D”.
Contact & links
- Lab address: Tissue engineering and Biomaterials Lab, Department of Human structure and repair, Ghent University, UZ Gent campus, MRB3, The Core, C. Heymanslaan 10, 9000 Gent, Belgium
- Tissue Engineering and Biomaterials Research Group
- FLIMagin3D
- Google Scholar
- Gabriele Ferrari is interested to receive invitations for presentations or talks