New microscope for spatial proteomics available @ VIB Proteomics Core

Spatial proteomics was selected as method of the year in 2024 by Nature. The VIB Proteomics Core agrees with that choice, and therefore invested in a brand new Leica LMD7 laser capture microscope, which was co-funded by the VIB Spatial Catalyst, the VIB Bioimaging Core Ghent, and the UZ Ghent Department of Pathology. The LMD device enables high-precision dissection of regions of interest for further spatial omics analysis. The VIB Proteomics Core optimized and implemented methods for mass spectrometry-based (unbiased), deep proteomic profiling of low-input LMD tissue samples (both fresh and FFPE). Using LCM in combination with mass spectrometry can be crucial in understanding molecular heterogeneity of (solid) tumors and their environment, for example.

For more information on the spatial proteomics workflow, contact Simon Devos (simon.devos@vib-ugent.be; recently appointed as new head of the VIB Proteomics Core). For general information on spatial omics and booking the device, contact Evelien Van Hamme (evelien.vanhamme@vib.be; head of the VIB Spatial Catalyst).