dr. Anne-Sophie Bamelis (MD)
Neurosurgical Resident - Department of Neurosurgery - UZ Gent
Doctoral fellow – Research Group 4Brain, Department of Head and Skin – UGent, Faculty of
Medicine and Health Sciences
Principal Investigator: prof. Robrecht Raedt (PhD)
Research focus
High-grade glioma (HGG) is the most aggressive and most common malignant primary brain tumor, affecting both adults and children. My research topic is brain tumor cell motility. HGG cells are known to infiltrate and migrate outside the visible tumor margins, sometimes even to distant locations within the brain, i.e. the subventricular zone (SVZ). By moving away from the primary tumor, these migratory cells are not targeted by local therapy, leading to tumor progession.
I aim to understand the cues for HGG cell migration as HGG cell motility may provide an innovative therapeutic opportunity. By synthetically administering migratory cues, tumor cells can be misled to a location of choice and there targeted by local therapy. In short, the tumor is attracted to be killed, a principle that we named ‘motility trapping’. The goal of this innovative strategy is to hinder tumor progression and enhance local therapy.
Biography
Dr. Anne-Sophie Bamelis graduated summa cum laude as a medical doctor in 2022 at Ghent University. Subsequently, she enrolled in specialist training to become a neurosurgeon at Ghent University Hospital. She has a specific interest in (pediatric) neuro-oncology.
Starting from October 2024, she will start her PhD research, focusing on developping motility trapping for high-grade glioma. Dr. Bamelis is a member of the Belgian Association for Neuro-Oncology (BANO) and European Society for Paediatric Oncology (SIOP).
Contact & links
- Lab address: 4Brain, Department of Head and Skin, Campus UZ Gent, C. Heymanslaan 10, The Core, ingang 37, 9000 Gent, Belgium
- Anne-Sophie Bamelis is interested to receive invitations for presentations or talks