prof. Tim De Meyer (PhD)
Prof. Tim De Meyer (PhD)
Principal investigator - BIOBIX - FBW (UGent)
Associate professor (Faculty of Bioscience Engineering, UGent) - chairman partner (Bioinformatics Institute Ghent)
Research focus
The core expertise of Tim De Meyer's group at the BIOBIX lab is the development and application of novel data-analytical methods for omics data. The current focus of his group's cancer related research is dysregulation of allele-specific expression (particularly imprinting) in cancer and omics-based biomarker discovery. We are always open for collaboration requests.
Research team
- prof. Tim De Meyer - PI, associate professor
- dr. Louis Coussement (PhD) - postdoctoral fellow
- Cedric Stroobandt - doctoral fellow
- Floris Voorthuijzen - doctoral fellow
- Femke De Graeve - doctoral fellow
- Jeroen Galle - bioinformatician
Key publications
- Challenges and emerging strategies for genome-wide evaluation of loss of imprinting in cancer. Br. J Biomed Sci 2026
- Comprehensive analysis of the melanoma DNA methylome identifies LY75 methylation as an independent marker predicting poor clinical outcome. J Invest Dermatol 2026
- Renal cell carcinoma detection: a systematic review in diagnostic urinary biomarkers. BMC Cancer 2025
- Population-level allelic dispersion modeling by maelstRom yields genome-wide maps of allele-specific dysregulation during early carcinogenesis. GigaScience 2025
- Characterization of loss-of-imprinting in breast cancer at the cellular level by integrating single-cell full-length transcriptome with bulk RNA-seq data. Biomolecules 2024
- Loss-of-imprinting of HM13 leads to poor prognosis in clear cell renal cell carcinoma. Biomolecules 2024
Clinically relevant aberrant Filip1l DNA methylation detected in a murine model of cutaneous squamous cell carcinoma. EBioMedicine. PMID: 34000624. 2021
MEXPRESS update 2019. NAR. 2019.
Analysis of DNA methylation in cancer: location revisited. Nat Rev Clin Oncol. 2018.
A comprehensive overview of genomic imprinting in breast and its deregulation in cancer. Nat Commun. 2018.
Contact & links
- Lab address: BIOBIX - Coupure Links 653, 9000 Gent