Laure De Pryck
Doctoral fellow - Lab of Nico Callewaert, Center for Medical Biotechnology – VIB-Ugent (Faculty of Science)
Principal investigators: prof. Nico Callewaert (PhD) & dr. Nele Festjens (PhD)
Research focus
CAR-T cell therapy has recently revolutionized the field of cancer immunotherapy. In this application, a patient’s own immune cells are engineered to allow them to recognize cancer cells when brought back into the patient. Despite some great successes in the treatment of blood cancers, the therapy is still faced with a lot of obstacles in order to become effective for the treatment of solid tumors. One major limiting factor is the immunosuppressive tumor microenvironment.
In our project, we will use genome engineering techniques, such as CRISPR-Cas9, to alter immunosuppressive pathways in the CAR-T cells.
Contact & links
- Lab address: VIB Medical Biotechnology Center, Technologiepark-Zwijnaarde 75, 9052 Gent, Belgium
- Callewaert lab
- Center for Medical Biotechnology – VIB
- Laure De Pryck is interested to receive invitations for talks or presentations