dr. Laura Guerrero (PhD)

Postdoctoral researcher - Lab for Leukemia Therapy Resistance (Center for Medical Genetics)
Department of Biomolecular Medicine, Faculty of Medicine and Health Sciences, Ghent University
Principal investigator: prof. Panos Ntziachristos (PhD)
Research focus
In the Ntziachristos group, our research is dedicated to T-cell Acute Lymphocytic Leukemia (T-ALL) therapy resistance. T- ALL constitutes 15% of pediatric ALL cases and 25% of ALL cases in adults. The existing therapy for T-ALL is associated with significant toxicity and resistance, especially in relapsed cases, emphasizing the urgent need for innovative and enhanced treatments. My research focuses on comprehending the molecular mechanisms underlying T-ALL. Particularly, I apply my experience in proteomics and in metabolism to better understand metabolic dysregulation in T-ALL, ultimately to investigate alternative therapies effective in aggressive T-ALL cases resistant to current therapies.
Biography
I completed my PhD in Molecular Biosciences at the Autonomous University of Madrid in 2023. During my doctoral studies, I worked at the Functional Proteomics Laboratory of the National Center for Biotechnology (Madrid), where my research focused on the application of mass spectrometry-based proteomics to study the progression of liver pathologies, including cirrhosis, liver cancer, and rare liver diseases, with a special focus on metabolic alterations.
Contact & links
- Lab address: Ghent University, Department of Biomolecular Medicine, Medical Research Building 2 (MRB2), entrance 38, Corneel Heymanslaan 10, 9000 Ghent, Belgium
- Ntziachristos Lab
- Laura Guerrero is interested to receive invitations for presentations or talks