dr. Kasper T. Christensen (PhD)

My research focuses on the interface between the epigenetic and RNA splicing landscapes in the development and severity of T-cell acute lymphoblastic leukemia. Our previous research has indicated that the demethylase JMJD3 that removes suppressive epigenetic marks is essential for T-ALL development and that components of the PRC2 complex that deposits these repressive methyl groups are often aberrantly spliced in T-ALL.
My research aims to characterize the perturbed splicing of PRC2 components and investigate the therapeutic potential in combining inhibitors of JMJD3 with inhibitors of splicing.
 

I have a bachelors and masters degree in molecular biology from Aarhus University Denmark. I wrote my PhD at KU Leuven on the hepatitis C virus epidemic in Flanders using 300 blood plasma samples from Leuven, Genk, and Antwerp by optimizing a combined wet- and dry-lab workflow for hypervariable viral species coupled to a maximum likelihood phylogenetic cluster transmission analysis.
 

• Lab address: Ghent University, Department of Biomolecular Medicine, Medical Research Building 2 (MRB2), entrance 38, Corneel Heymanslaan 10, 9000 Ghent, Belgium
• Ntziachristos Lab
• Kasper Thorhauge Christensen is interested to receive invitations for presentations or talks