Thibault Lootens

CRIG member
Thibault Lootens

Doctoral fellow – Research Group 4Brain, Department of Head and Skin – UGent, Faculty of 
Medicine and Health Sciences
Doctoral fellow – Research Group SynBioC, Department of Sustainable Organic Chemistry 
and Technology – UGent, Faculty of Bioscience Engineering
Principal Investigators: prof. Robrecht Raedt (PhD) and prof. Christian Stevens (PhD) 


Research focus

Glioblastoma (GBM) is known as the most aggressive and most common malignant primary brain tumor. There is an unmet need for alternative solutions, as therapeutic advances have been marginal over the past decades. The lack of effective treatments is due to inter- and intratumor heterogeneity, the complex tumor microenvironment (TME) and the blood-brain barrier. Current standard of care focusses on a one-dimensional approach, neglecting the complex interplay between cancer cells and their environment.
The goals of my research are to characterize important cell types residing in this TME and clarify their crosstalk with other TME cells and GBM cells. This will be investigated using animal models of GBM, as well as patient samples, which will be obtained in close collaboration with UZ Gent. Gaining insight in this unique TME will be of great importance in the development of future therapies, ultimately improving patient survival.


  • In 2022 I obtained my Master of Science in Bioscience Engineering with a major in Cell and Gene Biotechnology at Gent University. 

Contact & links

  • Lab address: 4Brain, Department of Head and Skin, Blok B, entrance 36, Corneel Heymanslaan 10, 9000 Gent
  • LinkedIn
  • Thibault Lootens is interested to receive invitations for presentations or talks