prof. Christian Stevens (PhD)

CRIG group leader
Christian Stevens

Head of the SynBioC Research group
Full professor, Department of Sustainable Organic Chemistry and Technology
Director "Green Chemistry Ghent"

 

Research Focus

  • Synthesis of anti-metastatic compounds
  • Synthesis of blebbistatin analogues
     

Biography

Prof. Dr. Ir. Christian V. Stevens (°1965) is professor at the Department of Green Chemistry and Technology at the Faculty of Bioscience Engineering (Ghent University). He graduated at the same department as bio-engineer in chemistry in 1988 and obtainded a PhD in 1992 as fellow of the National Fund for Scientific Research. During his PhD he also worked as a research assistant of the University of Southern California (USC), Los Angeles, USA with Prof. C.E. McKenna.
After his PhD at Ghent University under the direction of Prof. N. De Kimpe, he did post-doctoral work at the Center for Heterocyclic Compounds at the University of Florida, USA under the direction of Prof. A. R. Katritzky as a NATO Research Fellow. He became group leader in the group of Prof. Katritzky in 1993. He returned as a postdoctoral fellow of the National Fund for Scientific Research. In 1994, he also made a short postdoctoral stay at the University of Alicante (Spain) under the direction of Prof. M. Yus.
In 1995, he became group leader of the National Fund for Scientific Research and became guest professor in 1997 at Ghent University. In 2000, he became professor at the current Faculty of Bioscience Engineering and developed the research group SynBioC of which he is the director. Since 2014, he is senior full professor.
 

Research team

Key publications

  • Cytosolic delivery of gadolinium via photoporation enables improved in vivo magnetic resonance imaging of cancer cells. Biomaterials Science (2020).  
  • Continuous-Flow Synthesis of Phenothiazine Antipsychotics: A feasibility Study. Eur. J. Org. Chem., 1350 -1354, (2019).    
  • Recovering Actives in Multi-Antitarget and Target Design of Analogs of the Myosin II Inhibitor Blebbistatin. Frontiers in Chemistry, 6, article number 179 (2018). 
  • 4-Fluoro-3’,4’,5’-trimethoxychalcone as a new anti-invasive agent. From discovery to initial validation in an in vivo metastasis model.  Eur. J. Med. Chem.  (2015).
  • Further studies on anti-invasive chemotypes: An excursion from chalcones to curcuminoids.  Bioorg. Med. Chem. Lett. (2015).
  • Chick heart invasion assay for testing the invasiveness of cancer cells and the activity of potentially anti-invasive compounds. Journal of Visualized Experiments, issue 100, article number e52792, June 2015.
     

Contact & links

  • Coupure links 653, B- 9000 Gent
  • SyncBioC