'Pharmacogenetics: do YOU have your DNA passport? ' - Seminar

Adverse drug reactions (ADRs) are responsible for 5-7% of hospitalizations each year. Interindividual variation in drug metabolism is contributing to this problem. DNA analysis of drug metabolizing enzymes, such as cytochrome P450 2D6 enzyme (CYP2D6), can predict the drugs metabolizing capacity of each individual.Ron Van Schaik (Department of Clinical Chemistry , Erasmus University Medical Center, Rotterdam) will discuss the use of the 'DNA-passport for medication', a genetic profile of drug metabolizing enzymes of the cytochrome P450 system, so that drug therapy can be adjusted to this personal DNA profile.This approach will decrease adverse drug reactions to improve effectivity of therapy. The question you thus have to ask yourselves: “Do YOU already have your DNA-passport?