'Next-generation bioconjugates for intra- and extracellular targeting' - Lecture

Lecture by prof. Christian P. R. Hackenberger (Humboldt Universität zu Berlin & Leibniz-Forschungsinstitut für Molekulare Pharmakologie, Berlin, Germany)

In this presentation, l will focus on the chemical modification of functional proteins for pharmaceutical and medicinal applications. In my laboratory, we use a combined approach of recently developed chemoselective reactions and enzymatic ligations, for instance the so-called P5- or Tub-tag®-labeling, for bioconjugation. By generating stable antibody-drug conjugates (ADCs), structurally defined multivalent scaffolds or cell-permeable antibodies via conjugating cyclic cell-penetrating peptides, we provide new modalities for most challenging pharmaceutical targets, including next generation cancer therapeutics or novel inhibitors against viral infections. 

• Hosts: prof. Annemieke Madder (PhD)
• When: September 22 2022 at 10:30
• Where: Lecture room 0.1, S4 ground floor, Campus Sterre, Krijgslaan 281, B-9000 Gent
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