Yanti De Visser

CRIG member
Yanti De Visser

Doctoral fellow - Lab Normal and Malignant Hematopoiesis - Center for Medical Genetics (Faculty of Medicine and Health Science, UGent)
Doctoral fellow - Lab for Precision Cancer Medicine - Translational Cell & Tissue Research Unit (Faculty of Medicine, KU Leuven)
Principal Investigators: prof. Pieter Van Vlierberghe (PhD) and prof. Frederik De Smet (PhD)


Research focus

Glioblastoma (GBM) is an extremely aggressive and hard to treat brain tumor. The tumor’s inter- and intrapatient variety, the presence of therapy-resistant cancer stem cells and the blood-brain barrier complicates treatment which results in a poor prognosis. Trials from the past 20 years all failed, highlighting the urge for clinically more beneficial therapies. The discovery of different tumor cell populations within a tumor, using next-generation sequencing methods, suggests that more clinical success will be achieved using multi-drug therapies selectively targeting the different populations. Therefore, tailoring the therapy to the patient’s sample will improve clinical benefit. The development of a functional diagnostic tool, based on drug-specific biomarker identification, can assist clinicians with their decision making. Ultimately, this will improve the overall survival of GBM patients but also help select relevant patients for future clinical trials, lowering the economic burden for companies to invest in GBM research. 

Contact & links

  • Lab address: Center for Medical Genetics Ghent, Lab of Normal and Malignant Hematopoiesis, Medical Research Building 2 (entrance 38, 1st Floor, Room 110.007),  Corneel Heymanslaan 10, 9000 Ghent, Belgium
  • Lab address: Translational Cell & Tissue Research Unit, Lab for Precision Cancer Medicine, O&N4 (5th floor, Room 05.417), Herestraat 49, 3000 Leuven, Belgium
  • LinkedIn 
  • Yanti De Visser is interested to receive invitations for presentations or talks