Sanne Van Campenhout

CRIG member
Sanne Van Campenhout


PhD student - Hepatology Research Unit, Department of Internal Medicine and Pediatrics, UGent 
PhD student – Gut-Liver Immunopharmacology Unit, Dept. of Basic and Applied Medical Sciences, UGent
Principal Investigators: prof. Hans Van Vlierberghe (MD, PhD) and prof. Lindsey Devisscher (PhD)

 

Research focus

Hepatocellular carcinoma (HCC) is a primary liver cancer most often occurring in a background of liver fibrosis (scar tissue) and related to a high cancer-related mortality worldwide. Diabetes, obesity and hepatic steatosis (fatty liver) are all risk factors for the development of HCC. Therefore, we focus on experimental research covering the complexity of these comorbidities using a combined diabetes-fatty liver disease-HCC mouse model.

More specific, we investigate the macrophage subset heterogeneity in experimental HCC induced by diabetes and non-alcoholic fatty liver disease. We explore the potential of shaping these macrophage phenotypes by targeting IRE1α to improve disease outcome.
 

Contact & links