prof. Ingeborg Goethals (MD, PhD)

CRIG group leader
Ingeborg Goethals

Head of Clinic - Department of Nuclear Medicine (Ghent University Hospital)
Full professor - Faculty of Medicine and Health Sciences (University Ghent)
Principal Investigator Nuclear Medicine - Neuro-Oncology Research Group Ghent University Hospital / University Ghent
Member of the Board of Governors- Belgian Association Neuro-Oncology (BANO)

 

Research focus

As a senior nuclear medicine physician, Ingeborg Goethals, participates in the multidisciplinary neuro-oncology and head and neck cancer research groups of the Ghent University Hospital/Ghent University. These research groups have a unique expertise in clinical and preclinical multimodality imaging of (high-grade) brain and head and neck tumours for (differential) diagnosis, biopsy guidance, radiation treatment planning and therapy response assessment. The preclinical work in brain and head and neck tumours is performed in collaboration with the INovative Flemish IN vivo Imaging TechnologY (INFINITY) lab, the preclinical core imaging facility of the Ghent University.
 

Biography

Ingeborg Goethals is trained at the Ghent University both as a neurologist and a nuclear medicine physician. In 2004, she successfully defended her Ph. D. thesis entitled: 'Exploration of the Prefrontal Cortex by means of Neuroactivation and Receptor Imaging Studies with Single Photon Emission Tomography'. She is a senior nuclear medicine physician at the department of nuclear medicine of the Ghent University Hospital. As a senior staff member, she is dedicated to conventional nuclear medicine, PET-CT imaging in oncology and inflammatory and infectious diseases, as well as PET and SPECT imaging of the brain with an emphasis on refractory epilepsy, cognitive impairment and dementia, brain and head and neck tumours. She is also the trainer of the residents-in-training for nuclear medicine at the Ghent University Hospital. She is also the principal investigator of research multimodality imaging of brain and head and neck tumours. She already published many original papers both in national and international journals (see PubMed for complete list of publications). She is also the promotor and supervisor of PhD students: working in the field of imaging of (neuro)oncology.
 

Research team

  • prof. Ingeborg Goethals - principal investigator, full professor
  • dr. Jeroen Verhoeven (PhD) - postdoctoral fellow
  • Marjan Acou - doctoral fellow
  • Arne Verhofstadt - medical student
  • Laura Pieters - medical student
  • dr. Veroniek Van Driessche (MD) - doctoral fellow
     

Key publications

  • 'A Perspective on the radiopharmaceutical Requirements for Imaging and Therapy of Glioblastoma'. Theranostics, 2021
  • 'Assessment of the effect of therapy in a rat model of glioblastoma using [18F]FDG and  [18F]FCho PET compared to contrast-enhanced MRI'. Plos One. 2021
  • '2-[18F]FELP, a novel LAT1-specific PET tracer, for the discrimination between glioblastoma, radiation necrosis and inflammation'. Nucl Med Bio. 2020
  • 'Cost-effectiveness of [18F]fluoroethyl-L-tyrosine for temozolomide therapy assessment in patients with glioblastoma'. Front. Oncol. 2019. 
  • ‘Technical feasibility of [18F]FET and [18F]FAZA PET guided radiotherapy in a F98 glioblastoma rat model’. Radiat Oncol., 2019. (PMID: 31146757)
  • ‘New fluoroethyl phenylalanine analogues as potential LAT1-targeting PET tracers for glioblastoma’. Sci. Rep., 2019 (PMID: 30814660)
  • ‘The path toward PET-guided radiation therapy for glioblastoma in laboratory animals: a mini review’. Front. Med., 2019. (PMID: 30761302)
  • ‘Magnetic resonance imaging-guided radiation therapy using animal models of glioblastoma’. Br. J. Radiol., 2019 (PMID: 30563357)
  • ‘Machine learning based brain tumour segmentation on limited data using local texture and abnormality’. Comput. Biol. Med., 2018 (PMID: 29763764)
  • ‘A feasibility study on adaptive 18F-FDG-PET-guided radiotherapy for recurrent and second primary head and neck cancer in the previously irradiated territory’. Strahlenther. Onkol., 2018 (PMID: 29556677)
     

Contact & links