Marieke Vromman

CRIG member
Marieke Vromman

Doctoral fellow - OncoRNALab, Center for Medical Genetics (UGent)
Principal investigator: prof. Jo Vandesompele (PhD)


Research focus

Circular RNAs (circRNA) are a growing class of non-coding RNAs. Their stable circulation in plasma and possible link with cancer makes them attractive for biomarker studies. Several pipelines and methods for circRNA discovery have been published but large-scale validation of the predicted circRNAs is lacking. 
My research is focused on in vitro validation of predicted circRNAs with a particular interest in circRNAs deregulated in cancer. Using this information and circRNA predictions on large-scale RNA sequencing datasets of thousands of cancer patients, cancer cell lines and healthy individuals; I will then build the most comprehensive cancer circRNA resource.



  • I obtained a Master of Science in Biomedical Sciences with a major in Medical Genetics (UGent, 2018).
  • Currently, I am a full-time doctoral researcher (Stichting tegen Kanker) at UGent.

Key publications

  • Validation of Circular RNAs Using RT-qPCR After Effective Removal of Linear RNAs by Ribonuclease R. Curr Protoc, 2021 
  • Closing the circle: current state and perspectives of circular RNA databases. Briefings in Bioinformatics, 2020.

Contact & links

  • Lab address: campus UZ Gent, Blok B, ground floor, room 100.017 (entrance 36),Corneel Heymanslaan 10, 9000 Ghent, Belgium
  • LinkedIn 
  • Twitter 
  • Marieke Vromman is interested to receive invitations for presentations or talks