Lien Provez

CRIG member
Lien Provez


Doctoral fellow – Lab Normal and Malignant Hematopoiesis, Center for Medical Genetics (Faculty of Medicine and Health Sciences, UGent)
Principal Investigator: prof. Pieter Van Vlierberghe (PhD)

 

Research focus

T-cell acute lymphoblastic leukemia (T-ALL) is a rare and aggressive cancer of precursor T- cells, most occurring in children. Nowadays, patients are treated with intensive chemotherapy. However, a significant number of patients relapse and become refractory to intensive treatment. Therefore, more effective and less toxic therapies are required. Lysine-specific demethylase 1 (LSD1) was described as a potential targeted therapy for T-ALL.
The focus of my research is to acquire a better understanding and to optimize the use of LSD1 inhibitors and other epigenetic drugs in T-ALL.
 

Contact & links

  • Lab address: Center for Medical Genetics Ghent, Lab of Normal and Malignant Hematopoiesis, Medical Research Building 2 (entrance 38, 1st Floor, Room 110.007),  Corneel Heymanslaan 10, 9000 Ghent, Belgium
  • Center for Medical Genetics Ghent 
  • LinkedIn 
  • ProGenTomics:  ProGenTomics is a UGent facility that provides multiple services within the field of proteomics. Our collaboration is focused on quantifying histone modifications via mass spec.
  • Lien Provez is interested to receive invitations for presentations or talks