Justine Aelvoet
Doctoral Fellow – Biopharmaceutical Technology Unit, Department of Pharmaceutics (UGent)
Principal investigator: Prof. Bruno G. De Geest (PhD)
Research focus
My research centers on creating non-viral strategies for in situ CAR T cell generation by delivering mRNA through lipid nanoparticles (LNPs). Situated at the intersection of nanomedicine and immuno-engineering, this work seeks to drive the development of next-generation cancer immunotherapies that offer greater safety, scalability, and cost-effectiveness compared to traditional viral vector-based methods.
Biography
Justine Aelvoet obtained her Master’s degree in Pharmaceutical Sciences at Ghent University in 2021. She is currently an FWO doctoral fellow in the Department of Pharmaceutics (Ghent University), where her research focuses on developing non-viral strategies for in situ CAR T cell generation.
Key publications
- A Genetically Encoded Endogenous Antibody Recruitment Strategy for Innate Immune-Mediated Killing of Cancer Cells. Adv Mater, 2025. (PMID: 39924815)
Contact & links
- Lab for Biopharmaceutical Technology, Faculty of Pharmaceutical Sciences, third floor, Ottergemsesteenweg 460, 9000 Ghent
- Justine Aelvoet is interested to receive invitations for presentations or talks