Jax educational seminars on mouse modeling in cancer research
Program
- 9:30 - 10:15 Predictive cancer models using PDX mice
- Coffee break
- 10:30 - 11:15 Humanized NSG mice for innovative preclinical research
- Coffee break
- 11:30 - 12:15 Introduction to mice for cancer immunotherapy
Location: Seminar room MRB2 (UZ campus entrance 38), UZ Gent, C. Heymanslaan 10, Ghent
Speaker: Kevin Lominac, PhD - Technical Information Scientist, The Jackson Laboratory
Subscription: please subscribe (for free) via this link (May 22 at latest)
More info on the individual seminars:
1. Predicitive cancer models using PDX mice
• Learn how more than 280 PDX models have been established in partnership with a consortium of cancer hospitals and clinical trial teams
• Appreciate how the diversity of the PDX program represents current patient demographics
• See how the genetics, pathology, and treatment response of PDX tumors re ect clinical observations
2. Humanized NSG mice for innovative preclinical research
• Key genetic components rendering NSG mice immunode cient
• The superiority of the NSG mouse as a platform for humanization
• Advantages and considerations for speci c NSG humanization protocols
• Data demonstrating preclinical applications of Hu-NSG mice
3. Introduction to mice for cancer immunotherapy
•Types of cancer immunotherapeutics that have been characterized and validated in mouse models
• Cutting-edge humanized mouse models that are the next generation platform for immuno-oncology