dr. Behrouz Hassannia (PhD)
Postdoctoral researcher, Ferroptosis and Inflammation Research (FAIR) team, Molecular Signaling and Cell Death Unit (VIB Inflammation Research Center, UGent Department of Biomedical Molecular Biology).
Principal Investigator: prof. Tom Vanden Berghe & prof. Peter Vandenabeele (PhD)
Postdoctoral researcher, University of Antwerp.
One of the key challenges in cancer research is how to effectively kill cancer cells while leaving the healthy cells intact. Cancer cells often have defects in cell death executioner mechanisms, which is one of the main reasons for therapy resistance.
Our research aims at targeting cell death pathways to kill cancer cells and limit the survival of drug-resistant cells. In particular, we study ferroptosis that is an iron-catalyzed necrosis characterized by lipid peroxidation of membrane of cells.
- Targeting ferroptosis to iron out cancer, Cancer Cell, 2019. (PMID: 31105042)
- Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma. The journal of clinical investigation, 2018. (PMID: 29939160)
- A real-time fluorometric method for the simultaneous detection of cell death type and rate. Nature protocols, 2016, (PMID: 27414760)