dr. Edith De Bruycker (PhD)
CRIG member
Postdoctoral researcher – Therapy and RNA Group GhenT (TaRGeT) , UGent Department of Biomolecular Medicine, Ghent University
Principal Investigator: Prof. Frauke Coppieters (MD, PhD)
Research focus
Inherited retinal diseases (IRDs) cover a diverse group of monogenic disorders characterized by gradual vision loss. In over fifty percent of all cases, the disorder can be diagnosed, which allows for therapeutic interventions. However, for several subtypes (e.g. dominant-negative effect) the established therapies are not effective.
My research project focuses on characterizing one of the factors causing such an IRD. So that alternative therapeutic approaches can be exploited using Antisense Oligonucleotides (ASOs) and the innovative nanobody-technology.
Key publications
- Orthogonal proteomics methods to unravel the HOTAIR interactome. Sci Rep, 2022. (PMID: 35087108)
Contact & links
- Lab address: Campus UZ Gent, C. Heymanslaan 10, MRB2, entrance 38, 9000 Gent, Belgium
- LinkedIn