dr. Sofie Van Dorpe (MD)

CRIG member
Sofie Van Dorpe

PhD Researcher – Laboratory of Experimental Cancer Research – UGent
Gynaecology Resident - Department of Uro-Gynaecology (UZ Gent)
Principal investigators: prof. An Hendrix (PhD) and prof. Hannelore Denys (MD, PhD) 


 

Research focus

Symbiosis between epithelial barriers and their microbial ecosystems has a major impact on local and systemic immune mechanisms, marked by influencing therapy response and clinical outcome in cancer patients. Gram+ and Gram- bacteria release bacterial extracellular vesicles (BEV), nanometer-sized membrane particles transporting nucleic acids, metabolites, proteins and endotoxins. We believe that circulating BEV are, at least partially, responsible for the interaction between three biological entities: the microbiome, the tumor, and the immune system.
 

Biography

Sofie Van Dorpe graduated in 2018 as Master of Medicine, magna cum laude, at Ghent University. After obtaining her degree as a medical doctor (MD), she initiated her training in Gynaecology-Obstetrics at Ghent University Hospital and started as doctoral fellow at the Laboratory for Experimental Cancer Research (LECR) at Ghent University.
 

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