dr. Edith De Bruycker (PhD)
Postdoctoral researcher – Therapy and RNA Group GhenT (TaRGeT) , UGent Department of Biomolecular Medicine, Ghent University
Principal Investigator: Prof. Frauke Coppieters (MD, PhD)
Research focus
Inherited retinal diseases (IRDs) represent a heterogeneous group of devastating disorders characterized by progressive vision loss, together affecting more than 5 million individuals worldwide. Approximately 40% of patients remain molecularly unsolved, and it is hypothesized that a proportion of these cases may be explained by variants in non-coding regions. However, the role of long non-coding RNA in retinal biology remains largely unexplored. My research project aims to elucidate the function of long non-coding RNA in the retina and their contribution to IRD pathogenesis. Insights gained from this research may also have broader implications for cancer research, as dysregulation of non-coding RNA is increasingly recognized as a key driver of tumor development and progression.
Key publications
- Orthogonal proteomics methods to unravel the HOTAIR interactome. Sci Rep, 2022. (PMID: 35087108)
Contact & links
- Lab address: Campus UZ Gent, C. Heymanslaan 10, MRB2, entrance 38, 9000 Gent, Belgium
- LinkedIn