Dieter Tulkens

CRIG member
Dieter Tulkens

Doctoral fellow - Department of Biomedical molecular biology – VIB-UGent
Principal investigator: prof. Kris Vleminckx (PhD) & prof. Pieter Van Vlierberghe (PhD)


Research focus

There is an absolute need for more pre-clinical models that are easily accessible for “a la carte” genetic tailoring. Our fast and efficient Xenopus tropicalis cancer model is well positioned between cell culture studies and mouse cancer models. Our ultimate aim is developing novel targeted cancer therapies. To achieve this, we use our cancer models for identification and validation of cancer vulnerabilities and dependencies.


* 2013-2017: Bachelor and Master of Science in bioscience engineering technology, Ghent University
* 2017-present: PhD student, Department of Biomedical molecular biology – VIB-UGent

*  BSCDB poster award 2019 (Liège, Belgium)
* International Xenopus Board poster price 2019 (Lutherstadt-Wittenberg, Germany)
* FEBS Journal poster price 2018 (Cavtat, Croatia)
* KVCV award 2017 (Ghent, Belgium)

Key publications

  • Maximizing CRISPR/Cas9 phenotype penetrance applying predictive modeling of editing outcomes in Xenopus and zebrafish embryos. Scientific reports, 2020
  • RBL1 (p107) functions as tumor suppressor in glioblastoma and small-cell pancreatic neuroendocrine carcinoma in Xenopus tropicalis. Oncogene, 2020

Contact & links

  • Department of Biomedical molecular biology, VIB-UGent, Technologiepark Zwijnaarde 71, 9000 Gent, Belgium
  • Irc Ugent
  • Researchgate
  • LinkedIn
  • Dieter Tulkens is interested to receive invitations for presentations or talks