'Nanomaterials for drug delivery and in vivo imaging' - Smart Cancer Nanomedicine lecture by prof. T. Lammers
Nanomedicines are 1-100(0) nm-sized carrier materials designed to improve the biodistribution and target site accumulation of systemically administered (chemo-) therapeutic drugs. By delivering drug molecules more efficiently to pathological sites, and by preventing them from accumulating in healthy tissues, nanomedicines are able to improve the balance between efficacy and toxicity. Nanomedicines rely on the Enhanced Permeability and Retention (EPR) effect for efficient target site accumulation, which is notoriously known to be highly variable, both in animal models and in patients. To tackle this high heterogeneity in EPR, and to improve the (pre-) clinical performance of cancer nanomedicines, we are working on “smart” systems and strategies to modulate and monitor tumor-targeted drug delivery.
In the lecture by prof. Twan Lammers (Department of Nanomedicine and Theranostics, Institute for Experimental Molecular Imaging, Center for Biohybrid Medical Systems, RWTH Aachen University Clinic, Aachen, Germany) , several of these strategies will be highlighted, including pharmacological and physical modulation of tumor blood vessels and the microenvironment, and theranostic concepts for individualized and improved nanomedicine treatment.
- Venue: Seminar Room 4, Faculty of Pharmaceutical Sciences, Ottergemsesteenweg 460, Ghent
- September 24th, 2018 at 1.30 PM.
- Registration not required
- Host & Contact: prof. Stefaan De Smedt
- Flyer