'Gene Dysregulation in Cancer: the View from Chromosome Neighborhoods' invited speaker seminar
Core regulatory circuits (CRCs) are an emerging new concept in gene regulation during development and normal cellular function and deregulated CRCs can lead to diseases including cancer. The talk will elaborate on this theme and the important role of enhancers in this process and novel insights into enhancer biology and technology for investigating enhancer driven CRCs.
The speaker, dr. Denes Hnisz, is a former team member of the Young lab (Boston, USA) and has an impressive track record in work on enhancers and gene regulation with a focus on cancer. These new insights have direct translational impact as several of the gene regulatory processes unravelled through his work are druggable targets e.g. through CDK inhibitors targeting RNA polymerase controlled processes of transcription initiation and elongation.
- Venue: Room 90.78.100.029, MRB2 (entrance 38), UZ Ghent
- Host: prof. Frank Speleman