Technician - Inflammation Research Center (IRC) - VIB-UGent
Principal investigator: prof. Geert Berx (PhD)
Melanocyte stem cells have the extraordinary ability to maintain differentiated cell populations by dividing and generating new cells. Unfortunately, these same qualities that melanocyte stem cells possess in respect to growth and survival are also found in cancer (stem) cells. Our research seeks to elucidate physiological molecular pathways and mechanisms that regulate stem cell homeostasis and melanocyte differentiation and how these 'stemness' regulating pathways become dysregulated in conversion to a malignant state.