Neuroblastoma is a pediatric cancer entity characterized by a low mutational burden, but a high frequency of chromosomal copy number alterations (CNAs).
I provide wet lab assistence for the in vitro functional characterization of novel candidate tumor suppressor genes and dependency genes in this disease of which the expression levels are altered through these CNAs.
I obtained a Master degree in Biology with a specialization in Molecular Biology and Physiology (1999).
After several years of technology development in a private company, I joined the department of Molecular Biomedical Research (now Inflammation Research Centre) in 2008. Main focus was the role of cell adhesion molecules in cancer.
In 2017, I became a member of the Center for Medical Genetics. I have extensive experience in cell culture, cloning, functional assays, technology development, …