dr. Anke Delie (MD)
Doctoral fellow - Faculty of Medicine and Health Sciences, UGent
Clinical Hematologist - Hematology Department, UZ Gent
Principal Investigator: prof. Tessa Kerre (MD, PhD)
Research focus
Allogeneic hematopoietic stem cell transplantation (HSCT) is a curative treatment option in patients with malignant and non-malignant hematological diseases. The introduction of reduced intensity conditioning (RIC) regimens and non-myeloablative (NMA) regimens as well as advances in donor selection and supportive care have led to a reduction in the treatment related morbidity and mortality associated with allogeneic HSCT, allowing an increasing number of patients to benefit from this treatment. Improving the safety and efficacy of HSCT remains an important goal for transplant physicians. Optimising conditioning regimens and identifying factors improving disease control and factors increasing transplant related toxicity offer the potential to improve overall patient care when undergoing allogeneic HSCT.
My research focusses on the use of Fludarabine in conditioning regimens prior to allogeneic stem cell transplantation. The aim is to further characterise the Fludarabine exposure in patients undergoing transplantation with Fludarabine with the ulitmate goal of defining and optimal exposure range to guide treatment.
With our research we hope to optimise patient management during their cell therapy based on the principle of precision medicine ensuring that all patients, regardless of comorbidities, can receive treatment that is both safe and effective.
Biography
- Master in Medicine, UGent (2005 – 2012)
- Master in Internal Medicine, with specialisation in Clinical Hematology, UGent (2012 – 2018)
- Hematology fellowship focussing on allogeneic stem cell transplantation, Hôpital Saint-Antoine, AP-HP Sorbonne Université (2018-2019)
- Clinical Hematologist, special focus in allogeneic stem cell transplantation and acute leukemia, Ghent University Hospital (2019-current)
- Board member of the Belgian Hemtology Society (2022-current)
Contact & links
- Lab address: Deparment of Hematology, Ghent University Hospital, Corneel Heymanslaan 10, 9000 Gent
- Anke Delie is interested to receive invitations for presentations or talks