prof. Jan Philippé (MD, PhD)

CRIG group leader
Jan Philippé

Senior full professor (part-time)
Laboratory of Hematology, UZ Gent / UGent 
Faculty of Medicine and Health Sciences

 

Research focus

Our research is focused on leukemias, mainly optimization of diagnostic procedures (cytomorphology, immunophenotyping and molecular analyses), or optimization of follow-up procedures (ao. minimal residual disease monitoring). A main interest in the exploration of the leukemic stem cell and its role in acute myeloid leukemia and multi drug resistance.

Biography

As MD, I specialised in laboratory medicine in Ghent University and the free University of Brussels, supervising the laboratory of hematology. I have been teaching in Ghent University, and Rwanda National University. I have been board member of ISAC and president of the Belgian Society of Cytometry. I represent the Ghent University Hospital as affiliated center within EUROFLOW

Research team

  • prof dr Jan Philippé - PI, senior full professor (part-time)
  • dr Karl Vandepoele - post-doctoral fellow
  • Barbara Denys - clinical biologist, doctoral fellow
  • Barbara Depreter - clinical biologist-in training, doctoral fellow
  • Sofie De Sy - technician
  • Annick Willems - technician

Key publications

  • Lipoprotein lipase in chronic lymphocytic leukemia: function and prognostic implications. Eur J Haematol 2016 (27504855)
  • Optimization and testing of dried antibody tube : The EuroFlow LST and PIDOT tubes as examples. J Immunol Methods 2017 (28341440)
  • Cancer-related mRNA expression analysis using a novel flow cytometry-based assay. Cytometry B Clin Cytom 2017(28980766)
  • Leukaemic stem cell load at diagnosis predicts the development of relapse in young acute myeloid leukaemia patients. Br J Haematol 2017(29076143)
  • RNA-based FLT3-ITD allelic ratio is associated with outcome and ex vivo response to FLT3 inhibitors in pediatric AML. Blood 2018 (29669779)
  • The long non-coding RNA landscape in juvenile myelomonocytic leukemia. Haematologica 2018 (29858388)
  • A case of chronic eosinophilic leukemia with secondary transformation to acute myeloid leukemia. Leuk Res Rep 2018 (29892549)
  • The light Chain IgLV3-21 defines a new poor prognostic subgroup in chronic lymphocytic leukemia : results of a multicenter study. Clin Canc Res 2018 (29945996)
  • Clinical implications of measurable residual disease in AML : review of current evidence. Crit Rev Oncol Hemat 2019 (30661650)

Contact & links

  • Laboratory of Hematology, Building 2P8 (Entrance 22), Ghent University Hospital, Corneel Heymanslaan 10, B-9000 Ghent
  • EUROFLOW
  • LinkedIn
  • prof. Philippé is interested to receive invitations for presentations or talks