dr. Parisa Norouzitallab (PhD)
Post-doctoral fellow (FWO) - Laboratory for Immunology and Animal Biotechnology , Laboratory of Aquaculture & Artemia Reference Center (Faculty of Bioscience Engineering, UGent)
Principal Investigator: prof. Peter Bossier (PhD)
Working also at:
Swedish University of Agricultural Sciences, Uppsala, Sweden.
Uppsala University, Uppsala, Sweden
In recent years our understanding of biological events have been significantly changed due to availability of new techniques and development of new knowledge. Over the past decade, using simple model organisms such as Drosophila and C. elegans, have become more popular due to their effortless husbandry and simple biological pathways. More recently an old cancer research model (Artemia), which is also known as sea monkey, has been considered as interesting model organism to study epigenetic modifications that are the result of changes in the environment, diet or microbial community. Considering Artemia as an extremophile, understanding the mechanisms by which the animals respond to changes and resist various adverse environmental conditions is very interesting. Artemia has a short generation time, and produces dormant eggs (cysts). Under normal environmental condition, Artemia produces live larvae but once the environment is adverse, the animals switch to producing highly resistant cysts. These cysts cannot be hatched and are highly resistance against most of the environmental cues including UV, heat, salinity shock and many others. In addition, the animals are invertebrates and lack adaptive immune system and therefore, are interesting models to understand the mechanisms behind innate immune activation and it’s memory.
My current research focus is to:
- Understand the mechanisms behind innate immune memory
- The mechanism behind cyst formation in Artemia
- Understanding the mechanisms behind the resistance of Artemia cysts against environmental cues.
Contact & links
- Laboratory for Immunology and Animal Biotechnology (ImBiTech), Department of Animal Production, Faculty of Bioscience Engineering, Ghent University, Coupure links 653, 9000 Ghent, Belgium
- Laboratory of Aquaculture & Artemia Reference Center (ARC), Department of Animal Production, Faculty of Bioscience Engineering, Ghent University, Coupure links 653, 9000 Ghent, Belgium