dr. Martina Fabiano (MD, PhD)

CRIG member
Martina Fabiano


Postdoctoral researcher - Laboratory of Experimental Cancer Research - Faculty of Medicine and Health Sciences, Ghent University
Principal Investigator: prof. An Hendrix (PhD)
 

Research focus

Bacteria release bacterial extracellular vesicles (BEVs), nanosized membrane-bound particles that transport a wide variety of molecules, including nucleic acids, metabolites, proteins, and endotoxins. In 2020, my host laboratory demonstrated, for the first time, that gut microbiota–derived BEVs can be detected in the bloodstream of patients with impaired intestinal barrier function, such as individuals with cancer or living with HIV (Tulkens et al., Gut, 2020). Building on this discovery and on my background in extracellular vesicle immune modulation, my postdoctoral project focuses on characterizing BEVs present in human body fluids, specifically stool and blood plasma samples, to better understand their molecular composition and functional impact within their physiological and pathological contexts.
 

Biography

  • 2015-2021: MD (Medical Doctor), Faculty of Medicine, University of Buenos Aires (UBA), Argentina
  • 2021-2025: PhD in Basic Medical Sciences, University of Buenos Aires (UBA), Argentina
  • 2025 – present: Postdoctoral Researcher, Laboratory of Experimental Cancer Research (LECR), Ghent University, Belgium
     

Key publications

  • Plasma extracellular vesicle surface-located GAS6/PROS1 and CD39/CD73 attenuate inflammation. Cell reports, 2025. (PMID: 40751911)
     

Contact & links