Lien Provez

CRIG member
Lien Provez


Doctoral fellow – Lab Normal and Malignant Hematopoiesis, Center for Medical Genetics (Faculty of Medicine and Health Sciences, UGent)
Principal Investigator: prof. Pieter Van Vlierberghe (PhD)

 

Research focus

T-cell acute lymphoblastic leukemia (T-ALL) is a rare and aggressive cancer of precursor T- cells, most occurring in children. Nowadays, patients are treated with intensive chemotherapy. However, a significant number of patients relapse and become refractory to intensive treatment. Therefore, more effective and less toxic therapies are required.
The focus of my research on the one hand is to acquire a better understanding and to optimize the use of the drug Decitabine in T-ALL and T-LBL, and on the other hand the epigenetic prediction of sensitivity towards the less toxic anthracycline variant aclarubicin in T-ALL.
 

Contact & links

  • Lab address: 
    Center for Medical Genetics Ghent, Lab of Normal and Malignant Hematopoiesis, Medical Research Building 2 (entrance 38,
    1st Floor, Room 110.007),  Corneel Heymanslaan 10, 9000 Ghent, Belgium
  • Center for Medical Genetics Ghent 
  • LinkedIn 
  • ProGenTomics:  ProGenTomics is a UGent facility that provides multiple services within the field of proteomics. Our collaboration is focused on quantifying histone modifications via mass spec.
  • Lien Provez is interested to receive invitations for presentations or talks