Charlotte Carlier

CRIG member

PhD student, laboratory of experimental surgery, UGent (Principal investigator: prof. dr. Wim Ceelen)

Research focus

  • Clinical trial (= OVip1) : "The effect of intraoperative intraperitoneal chemoperfusion to treat women with advanced or recurrent epithelial ovarian cancer: a randomized, controlled double-blind clinical trial"
  • Investigating the delivery, penetration depth and distribution of Pt in ovarian cancer tissues (human, mice)
  • Preclinical evaluation of Melflufen (J1) 

Key publications

  • C. Carlier, B. Laforce, S.J. Van Malderen, F. Gremonprez, R. Tucoulou, J. Villanova, O. De Wever, L. Vincze, F. Vanhaecke, W. Ceelen, Nanoscopic tumor tissue distribution of platinum after intraperitoneal administration in a xenograft model of ovarian cancer, Journal of pharmaceutical and biomedical analysis 131 (2016) 256-262.
  • C. Carlier, S. Strese, K. Viktorsson, E. Velander, P. Nygren, M. Uustalu, T. Juntti, R. Lewensohn, R. Larsson, J. Spira, E. De Vlieghere, W.P. Ceelen, J. Gullbo, Preclinical activity of melflufen (J1) in ovarian cancer, Oncotarget  (2016).
  • C. Carlier, S. Strese, K. Viktorsson, E. Velander, P. Nygren, M. Uustalu, T. Juntti, R. Lewensohn, R. Larsson, J. Spira, E. De Vlieghere, W.P. Ceelen, J. Gullbo, Preclinical activity of melflufen (J1) in ovarian cancer, Oncotarget  (2016).
  • E. De Vlieghere, C. Carlier, W. Ceelen, M. Bracke, O. De Wever, Data on in vivo selection of SK-OV-3 Luc ovarian cancer cells and intraperitoneal tumor formation with low inoculation numbers, Data Brief 6 (2016) 542-9.

Contact

Laboratory of experimental surgery, Building B, -1